Automated Dissection Chip

SKU: A1-AD-5PK-1 Category: Yeast Aging Assays Tag: Related-Three

APPLICATION

High-throughput replicative lifespan assay
Genetic screening for longevity
Proteomic screening for protein turnover and relocalization
Nutrient sensing and signaling pathways

Y-shaped Trap Option

Now, Y-shaped traps are available to ensure the assay starting from virgin cells
See our flyer for more information

Choose options

Add to quotation

$800.00

Quantity: 5 Chips

In Stock – Usually shipped next day

Available through global distributors

Features
Specifications
Documentations
Videos
Publications

Features

Capable of trapping over 10,000 single yeast cells
Tracks whole lifespan of over 10,000 yeast cells for 20 different strains in 3 days of culturing
Daughter are automatically separated from their mothers to reduce labor and time cost
Customization for trap dimension and substrate are available

BENEFITS

Time effective: analysis only takes 3 days
Reduces labor: automated tracking of entire lifespan
High-throughput: processes over 10,000 single-cells for 20 different strains
Imaging capability: high resolution fluorescent imaging

OPERATION AND ANALYSIS

Continuous live cell imaging of budding yeasts throughout their entire lifespans
Compatible with high resolution fluorescent imaging microscopes for single-cell tracking
Continuous supply of fresh media minimizing variations introduced by environment
Consistent results with conventional microdissection approach

Specifications

Material: Biocompatible polymer
Packaging: 4pk/Cs, individually packed
Size of Device: 75 mm (length), 25 mm (width), 4 mm (height)
Substrate: #1 glass coverslip (0.13-0.16 mm thickness)
Number of Trap: Total 18,000 traps (900 traps x 20 separate channels)
Number of Inlet: 20 media & cells inlets

Documentations

Automated Dissection Chip Flyer (489 KB)
A1 Cell Imaging System Flyer (291 KB)
Automated Dissection Chip Protocol (122 KB)

Videos

AD-Chip Replicative Lifespan Assay

Publications

High-throughput analysis of yeast replicative aging using a microfluidic system. (2015) Proceedings of the National Academy of Sciences, 112(30), 9364–9369. doi:10.1073/pnas.1510328112